Dr. Moien Kanaan

Dr. Moien Kanaan is an associate professor of molecular genetics at the life science department, Bethlehem University. He is currently the director of the Hereditary Research lab.

Education:

University of Baghdad Baghdad, Iraq  -  B.A. Nutrition, 1979
University of Arizona Tuscon, Arizona  -  M. Sc. Microbiology, 1984
Ohio State University Columbus, Ohio  -  Ph.D. Genetics, 1992

Experiance:

1979-1981      Lab Assistant, Life Sciences, Bethlehem Un

1981-1984      Study Leave, M. Sc Microbiology ,University of Arizona, USA

1984-1987      Instructor, Life Sciences, Bethlehem University, USA

1987-1992      Study Leave, Ph. D Molecular Genetics

                       Ohio State University, USA

1992-1998      Assistant Professo - Department of Life Sciences

                       Bethlehem University Bethlehem, Palestinian Authority

1998-Present  Associate Professor - Department of Life Sciences

                        Bethlehem University - Bethlehem, Palestinian Authority

1999-2000      Fullbright Fellow and Visiting Associate Professor

                        Department of Medicine , Department of Medical Genetics

                        University of Washington, Seattle

2000-Present Science Associate Staff, University of Toronto and Mount Sinai Hospital,

                        Toronto Canada

2000-Present  Affiliated Associate Professor , University of Washington

                        Seattle, USA.

.

Publications:

  • Olson GB. Kanaan MN. Kelly LM, Jones JF. (1987) Correlation between allergy and persistent Epstein-Barr virus infection in chronic-active Epstein-Barr virus-infected patients, J Allergy Clin Immunol 78: 308-314.

  • Olson GB, Kanaan MN, Kelly LM, Jones JF. (1988) Specific allargen-induced Epstein-Barr nuclear antigen-positive B-cells from patients with chronic-active Epstein-Barr virus nuclear antigen-positive B-cells from patients with chronic-active Epstein-Barr virus infections. J. Allergy Clin Immunol 78: 315-320.

  • Kanaan MN, Marzluf GA. (1991) Mutational analysis of the DNA binding domain of the CYS-3 regulatory gene. Mol Cell Biol 11: 4356-4359.

  • Kanaan MN, Marzuluf GA (1992) The DNA binding domain of the CYS3 regulatory gene is bipartite. J Biochem 31: 3197-3203.

  • Kanaan MN, Marzulf GA (1993) The positive acting regulatory protein CYC3: Nuclear localization, autogenous control and regions required for transcriptional activation. Mol Gen Genet 239: 334-344.

  • Muller F, Kruger D, Sattelgger E, Hoffmann B, Wende A, Ballario P, Kanaan M, Barthelmess IB (1995). Cpc-2, a gene encoding a highly conserved protein with a repetitive segmental structure involved in general amino acid control and female fertility. Mol Gen Genet. 248: 162-173.

  • Marzluf GA, Kanaan MN. (1995) Molecular analysis of DNA-binding, trans-acting regulatory proteins. Bethlehem J 14: 21-33.

  • Kanaan MN (1996) Can we control MRSA-strains in hospitals in Palestine? Bethlehem J 15: 106-113.

  • Kanaan MN. (1997) Molecular strategies for typing and properties of epidemic methicillin-resistant Staphylococcus aureus. J Hos Infec 15: 12-17.

  • Kanaan MN. (1999) High concordance between quantitative antibiogram and pulse field macrorestriction analysis in typing methicillin-resistant Staphylococcus aureus. Epidemioloy 23:145-148

  • Kanaan MN, Shaen H, Morrow J, Sobe T, King M-C, Avraham KB, Lynch ED. (1999) Genetic analysis of hearing loss in Palestinian kindreds. Amer Soc Human Genet, Abstract.

  • Sobe T, Vreugde S, Shahin H, Berlin M, Kanaan M, Yaron Y, Orr-Urtreger A, Frydman M, Shohat M, Avraham KB (2000). Prevalence and expression of inherited connexin 26 mutations associated with nonsyndromic hearing loss in the Israeli population, Human Genetic:106,50-57.

  • Hashem Shahin, Tom Walsh, Tama Sobe, Eric Lynch, Mary-Claire King,
    Karen B. Avraham, , Moien Kanaan (2002) Genetics of congenital deafness in the Palestinian population:Multiple connexin 26 alleles with shared origins in the Middle East. Hum.Genet.110:284-289

  • Abd El-latif, M ,Filon D, Oppenheim A, Kanaan M (2002). IVS1-6 accounts for half of the thalassemia chromosomes in the Palestinian population of the mountain region.
    Hemoglobin .26 ,1:33-40

  • Aoi Nakano, Gilles G. Lestringant, Tamar Paperna, Reuven Bergman, Ruth Gershoni, Philippe Frossard, Moien Kanaan, Guerrino Meneguzzi, Gabriele Richard, Ellen Pfendner, Jouni Uitto, Leena Pulkkinen, Eli Sprecher (2002) Junctional epidermolysis bullosa in the Middle East :clinical and genetic studies in a series of consanguinous families. J.Am.Acad.Dermatol :46,4, 510-5

  • Ingrid Zwaenepoel, Mirna Mustapha, Michel Leibovici, Elisabeth Verpy, Richard Goodyear, Xue Zhong Liu, Sylvie Nouaille, Walter E. Nance, Moien Kanaan, Fredj Tekaia, Jacques Loiselet, Jean Weissenbach, Marc Lathrop, Guy Richardson and Christine Petit (2002) Otoancorin, an inner ear protein restricted to the interface between the apical surface of sensory epithelia and their overlying acellular gels, is defective in autosomal recessive deafness DFNB22.PNAS:99,9,6240-6245.
    Tom Walsh, Vanessa Walsh, Sara Vreugde, Ronna Hertzano, Hashem Shahin, samnder Haika, Ming K.Lee, Moien Kanaan, Mary-Claire King and Karen Avraham. (2002). From flies to our ears: mutations in a human class 111 myosin cause progressive nonsyndromic hearing loss DFNB30. PNAS:99,7518-7523.

  • Novel PDGF_R antisense encapsulated in polymeric nanospheres for the treatment of restenosis.(2002) H Cohen-Sacks, Y Najajreh,, V Tchaikovski, G Gao, V Elazer, R Dahan, I Gati, M Kanaan, J Waltenberger3 and G Golomb. Gene Therapy :9, 30-39

  • Green GE, Mueller RF, Cohn ES, Avraham KB, Kanaan M, Smith RJH(2003).Audiological manifestations and features of Connexin 26 deafness. Audiolog Med:1:5-11.

  • Moien kanaan and Hashem Shahin. (2003).Guidelines for Palestinian Families with Hearing Loss Affected Kids, Bethlehem University Publication.

  • Epidermolysis bullosa simplex in Israel: clinical and genetic features (2003). Ciubutaro D, Bergman R, Baty D, Indelman M, Pfender E, Petronius D, Moualem H, Kanaan M, Ben Amitai D, McLean WHI, Uitto J, Sprecher E J, Arch Dermato:139,498-505

  • Lionel F. Schnur, Abdelmageed Nasereddin, Carol L. Eisenberger, Charles L. Jaffe, Mustafa El Fari, Kifaya Azmi, Gerlind Anders, Mireille Killick-Kendrick, Robert Killick-Kendrick, Jean-Pierre Dedet, Francine Pratlong, Moien Kanaan, Tamar Grossman, Raymond L. Jacobson, Gabrielle Schonian, And Alon Warburg (2004) Multifarious Characterization Of Leishmania Tropica From A Judean Desert Focus, Exposing Intraspecific Diversity And Incriminating Phlebotomus Sergenti As Its Vector, Am. J. Trop. Med. Hyg.,70(4), pp. 364–372

  • F J del Castillo, M Rodrý´guez-Ballesteros, A lvarez, T Hutchin, E Leonardi, C A de Oliveira,H Azaiez, Z Brownstein, M R Avenarius, S Marlin, A Pandya, H Shahin, K R Siemering, D Weil,W Wuyts, L A Aguirre, Y Martý´n, M A Moreno-Pelayo, M Villamar, K B Avraham, H-H M Dahl, M Kanaan,WE Nance, C Petit, R J H Smith, G Van Camp, E L Sartorato, A Murgia, F Moreno, I delCastillo (2005). A novel deletion involving the connexin-30 gene, del(GJB6-d13s1854), found in trans with mutations in the GJB2 gene(connexin-26) in subjects with DFNB1 non-syndromic hearing impairment
    J Med Genet;42:588–594.

  • Analysis of the emergence visceral leishmaniasis in Central Israel by molecular subtyping (2005)
    Abedelmajeed Nasereddin, Gad Baneth, Gabriele Schönian ,Moein Kanaan, and Charles L. Jaffe,
    submitted

  • Tom Walsh, Amal Abu Rayan, Judeh Abu Sa’ed, Hashem Shahin,Ming K. Lee2, Koret Hirschberg4, Mustafa Tekin5, Karen B. Avraham3, Mary-Claire King and Moien Kanaan (2005)GENOMIC ANALYSIS OF A HETEROGENEOUS Mendelian Phenotype: Multiplenovel Alleles For Inherited Hearing Loss In The Palestinian Population, Human genomics .J submitted